Wound Care Applications
AMNIOTIC MEMBRANE PATCHES?
Amniotic membrane, or amnion, is the innermost layer of the placenta and consists of a thick basement membrane and an avascular stromal matrix. Amniotic membrane transplantation has been used as a graft or as a dressing in different surgical sub-specialties.
Key Attributes of Amniotic Patches:
Variety of Growth Factors
Reabsorbs in the body
Platelet-rich plasma (PRP) is plasma with many more platelets than what is typically found in blood. A high-quality PRP system can concentrate platelets 6-10 times greater than what is usual in blood.
The platelets contain growth factors such as platelet-derived growth factor, epidermal growth factor (EGF), fibroblast growth factor, and connective tissue growth factor. Blood is drawn from the patient and is then placed in a centrifuge to spin at high speeds. This allows the platelet-rich plasma to separate from the blood.
Amniotic membrane patches are used in many parts of the world as a temporary dressing for clean superficial wounds such as partial-thickness burns, donor sites, and freshly excised burns awaiting donor site availability. Amniotic membrane is generally procured fresh and used after brief refrigerated storage. It can also be used in a nonviable state after preservation with glycerol. It has been treated with silver to facilitate control of bacterial overgrowth. Amnion does not vascularize but still can provide effective temporary wound closure.
Patch Sizes Available:
Our Amniotic Membrane Patches are an easy to handle, dry graft that re-hydrates within the wound setting. They are highly concentrated and can be used to cover wounds and surgical sites, nerve wraps, tendon wraps, adhesion barriers, and to lay over surgical hardware and implants such as pacemakers, to prevent the surrounding tissue to adhere to the implant with scar tissue.
In the case of wound care, PRP is injected directly into the affected area. Targeted delivery of these growth factors to injured tissues can accelerate and promote the healing cascade within your body.
PRP treatments for wound care are becoming more common and a viable choice amongst patients who are looking for shortened hospital stays, cost efficient/shortened treatments, and an improvement in one’s quality of life.
The anti-inflammatory properties of PRP play an important role in wound healing. PRP not only releases large quantities of platelet growth factors to enhance the healing process, it also possesses antimicrobial properties that may contribute to the prevention of infections.
Leukocytes are at high levels in PRP because the density of leukocytes are similar to that of the platelets. During the centrifuge process both platelets and leukocytes drop into the same layer of the centrifuge tube. Advantages of PRP for wound treatment include the biocompatible safety of using the patient’s own blood. As well as the significant clinical effectiveness and simple preparation, PRP treatments have become an ideal therapy in the treatment of chronic skin related wounds.